About 3 results found for searched term "Methotrexate metabolite" (0.132 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3262 | Methotrexate metabolite | Antifolate |
| DAMPA; NSC 131463 | ||
| Methotrexate metabolite is a dihydrofolate reductase potent inhibitor with an IC50 of 1 nM. | ||
| M13588 | Methotrexate disodium | Antifolate |
| Amethopterin disodium; CL14377 disodium; WR19039 disodium | ||
| Methotrexate (Amethopterin) disodium, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. | ||
| M49951 | Methotrexate hydrate | Antifolate |
| Amethopterin hydrate; CL14377 hydrate; WR19039 hydrate | ||
| Methotrexate hydrate is an antimetabolite and antifolate that inhibits dihydrofolate reductase, thereby preventing the conversion of folic acid to tetrahydrofolate and inhibiting DNA synthesis. In addition, Methotrexate hydrate is an immunosuppressant and antitumor agent used in studies related to rheumatoid arthritis and various cancers such as acute lymphoblastic leukemia. | ||
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